abstract：INTRODUCTION:Health care demand is increasing due to greater longevity of patients with chronic comorbidities. This increasing demand is occurring in a setting of resource scarcity. To address these changes, high-value care initiatives, such as telemedicine, are valuable resource-preservation strategies. This study int...

journal_title：Clinical cardiology

authors： Chorin E,Padegimas A,Havakuk O,Birati EY,Shacham Y,Milman A,Topaz G,Flint N,Keren G,Rogowski O

更新日期：2016-11-01 00:00:00

abstract：:Paravalvular regurgitation (PVR) remains one of the drawbacks of transcatheter aortic valve implantation (TAVI). Details of percutaneous closure (PCC) of PVR after TAVI remain obscure. We aimed to explore the patient characteristics, procedural details, closure devices used, and outcomes of PCC after TAVI. A systemati...

journal_title：Clinical cardiology

authors： Ando T,Takagi H,ALICE (All-Literature Investigation of Cardiovascular Evidence) Group.

更新日期：2016-10-01 00:00:00

abstract：:Several studies have investigated the role of physical fitness in atrial fibrillation (AF), but the results remain controversial. We aimed to estimate the association between physical fitness and risk of AF. We comprehensively retrieved data from the Cochrane Library, PubMed, and Embase databases until February 29, 20...

journal_title：Clinical cardiology

authors： Zhu W,Shen Y,Zhou Q,Xu Z,Huang L,Chen Q,Hong K

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease, insulin resistance (IR), and obesity frequently coexist with type 2 diabetes mellitus (DM), but it is uncertain whether these risk factors for vascular disease contribute to a change in atherosclerosis over time, independently of DM status. HYPOTHESIS:We hypothesized that t...

journal_title：Clinical cardiology

authors： Sung KC,Ryu S,Lee JY,Lee SH,Cheong ES,Wild SH,Byrne CD

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Low levels of high-density lipoprotein cholesterol (HDL-C; <40 mg/dL) are associated with increased risk of cardiovascular events, but it is unclear whether lower thresholds (<30 mg/dL) are associated with increased hazard. HYPOTHESIS:Very low levels of HDL-C may provide prognostic information in acute coro...

journal_title：Clinical cardiology

authors： Hagström E,Roe MT,Hafley G,Neely ML,Sidhu MS,Winters KJ,Prabhakaran D,White HD,Armstrong PW,Fox KA,Ohman EM,Boden WE,TRILOGY ACS Investigators.

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Following successful cavotricuspid isthmus (CTI) ablation during typical atrial flutter (AFL), anticoagulation therapy is usually withdrawn. However, potential subsequent atrial fibrillation (AF) in these patients may increase embolic risk in the long term. Embolic rates in this setting have not been clearly...

journal_title：Clinical cardiology

authors： Expósito V,Rodríguez-Entem F,González-Enríquez S,Veiga G,Olavarri I,Olalla JJ

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Compared with medical therapy, percutaneous coronary intervention (PCI) does not reduce mortality or myocardial infarction in patients with stable angina. Therefore, PCI should be guided by refractory anginal symptoms and not just lesion characteristics. HYPOTHESIS:We hypothesized that angiographic lesion c...

journal_title：Clinical cardiology

authors： Atreya AR,Sivalingam SK,Arora S,Kashef MA,Fitzgerald J,Visintainer P,Lotfi A,Rothberg MB

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF), a disease of the elderly, occasionally occurs at younger age. Pathophysiology of AF in younger patients is diverse, including channelopathies and cardiomyopathies. Data on the significance and complications of AF in young patients are scarce. HYPOTHESIS:Atrial fibrillation is the f...

journal_title：Clinical cardiology

authors： Wutzler A,von Ulmenstein S,Attanasio P,Huemer M,Parwani AS,Völk K,Blaschke F,Boldt LH,Haverkamp W

更新日期：2016-04-01 00:00:00

abstract：:There is an apparent benefit with extension of dual antiplatelet therapy (DAPT) beyond 1 year after implantation of drug-eluting stents (DES). Assessment by a Double Randomization of a Conventional Antiplatelet Strategy vs a Monitoring-Guided Strategy for Drug-Eluting Stent Implantation, and of Treatment Interruption ...

journal_title：Clinical cardiology

authors： Collet JP,Silvain J,Kerneis M,Cuisset T,Meneveau N,Boueri Z,Barthélémy O,Rangé G,Cayla G,Belle EV,Elhadad S,Carrié D,Caussin C,Rousseau H,Aubry P,Monségu J,Sabouret P,O'Connor SA,Abtan J,Saint-Etienne C,Beygui F,

更新日期：2016-04-01 00:00:00

abstract：:Ranolazine utilization in the management of refractory angina has been established by multiple randomized clinical studies. However, there is growing evidence showing an evolving role in the field of cardiac arrhythmias. Multiple experimental and clinical studies have evaluated the role of ranolazine in prevention and...

journal_title：Clinical cardiology

authors： Saad M,Mahmoud A,Elgendy IY,Richard Conti C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Patients with sinus node dysfunction (SND) have increased risk of atrial tachyarrhythmias, including atrial fibrillation (AF). To date, treatment patterns and outcomes of patients with SND and AF have not been well described. HYPOTHESIS:Patients with SND and AF have higher risk of adverse cardiovascular out...

journal_title：Clinical cardiology

authors： Jackson LR 2nd,Kim SH,Piccini JP Sr,Gersh BJ,Naccarelli GV,Reiffel JA,Freeman J,Thomas L,Chang P,Fonarow GC,Go AS,Mahaffey KW,Peterson ED,Kowey PR

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The role of warfarin in anterior ST-segment elevation myocardial infarction (STEMI) complicated by left ventricular (LV) dysfunction in patients treated with primary percutaneous coronary intervention (PCI) and dual antiplatelet therapy is unclear. Warfarin may prevent cardioembolic events but significantly ...

journal_title：Clinical cardiology

authors： Driesman A,Hyder O,Lang C,Stockwell P,Poppas A,Abbott JD

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Acute changes in high-sensitivity troponin T (hs-TnT) are induced by myocardial ischemia during exercise stress testing, but there are no reports of pharmacological stress testing. HYPOTHESIS:The pattern of troponin release by myocardial ischemia-induced pharmacological stress testing differs according to t...

journal_title：Clinical cardiology

authors： Wongpraparut N,Piyophirapong S,Maneesai A,Sribhen K,Krittayaphong R,Pongakasira R,White HD

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Radiation-treated head and neck cancer (HNC) patients are at high risk for developing radiation vasculopathy, as evidenced by an increased stroke risk. The benefits of screening and assessing the cardiovascular (CV) risk of HNC patients using carotid intima-media thickness (CIMT) ultrasound are not known. Ou...

journal_title：Clinical cardiology

authors： Jacoby D,Hajj J,Javaheri A,deGoma E,Lin A,Ahn P,Quon H

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:In patients with acute decompensated heart failure (ADHF), both natriuretic peptides and renal impairment predict adverse outcomes. Our aim was to evaluate the complementary prognosis role of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and the newly developed Chronic Kidney Disease Epidemiology Col...

journal_title：Clinical cardiology

authors： Flores-Blanco PJ,Manzano-Fernández S,Pérez-Calvo JI,Pastor-Pérez FJ,Ruiz-Ruiz FJ,Carrasco-Sánchez FJ,Morales-Rull JL,Pascual-Figal D,Galisteo-Almeda L,Januzzi JL

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The optimal strategy for treating late presenters of ST-elevation myocardial infarction (STEMI) remains uncertain. HYPOTHESIS:percutaneous coronary intervention (PCI) has a favorable effect on left ventricular (LV) remodeling and clinical outcomes in late presenters of STEMI. METHODS:Patients with STEMI wh...

journal_title：Clinical cardiology

authors： Fan Y,Bai X,Chen Y,Shen G,Lu Q,Wan Z,Zhou D,Shen Y,Ma A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:There are very sparse data on patient outcomes related to the use of extracorporeal membrane oxygenation (ECMO) prior to heart operation in children with congenital heart disease. This study was designed to evaluate this association using the Pediatric Health Information System (PHIS) database. HYPOTHESIS:W...

journal_title：Clinical cardiology

authors： Gupta P,Robertson MJ,Beam BW,Rettiganti M

更新日期：2015-02-01 00:00:00

abstract：:Individuals age >65 years represent the fastest-growing subpopulation in the United States. Although these individuals with the highest cardiovascular risk profile would be anticipated to be the most aggressively treated, paradoxically, treatment and baseline risk are inversely related. Presumably, the elderly populat...

journal_title：Clinical cardiology

authors： Wilmot KA,Khan A,Krishnan S,Eapen DJ,Sperling L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Primary percutaneous coronary intervention (PCI) is the most common method of reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) in the United States. The intersection between processes of care and performance measures such as door-to-balloon (D2B) times and clinical trials evalu...

journal_title：Clinical cardiology

authors： Jones WS,Clare RM,Chiswell K,Perera D,French JK,Kumar AS,Blaxill J,Pijls N,Mills J,Ohman EM,Patel MR

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Total serum transforming growth factor-beta 1 (tsTGF-β1) is increased in patients with Marfan syndrome (MFS), but it has not been assessed in thoracic aortic aneurysm and dissection (TAAD), Loeys-Dietz syndrome (LDS), and bicuspid aortic valve disease (BAVD). HYPOTHESIS:tsTGF-β1 is increased in genetic aort...

journal_title：Clinical cardiology

authors： Hillebrand M,Millot N,Sheikhzadeh S,Rybczynski M,Gerth S,Kölbel T,Keyser B,Kutsche K,Robinson PN,Berger J,Mir TS,Zeller T,Blankenberg S,von Kodolitsch Y,Goldmann B

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Syncope is a common clinical problem with a variety of underlying mechanisms, some of which occur more frequently in 1 of the sexes or at a certain age. HYPOTHESIS:There may be clinically significant age- and gender-related differences in patients with unexplained syncope. METHODS:Five hundred seventy pati...

journal_title：Clinical cardiology

authors： Edvardsson N,Garutti C,Rieger G,Linker NJ,PICTURE Study Investigators.

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Congenital coronary-pulmonary fistulas (CPFs) are commonly unilateral, but bilateral and multilateral fistulas may occur. In multilateral CPFs, the value of a multidetector computed tomography (MDCT) imaging technique as an adjuvant to coronary angiography (CAG) is eminent. The purpose of this study was to d...

journal_title：Clinical cardiology

authors： Said SA,Nijhuis RL,Akker JW,Takechi M,Slart RH,Bos JS,Hoorntje CR,Houwelingen KG,Bakker-de Boo M,Braam RL,Vet TM

更新日期：2014-09-01 00:00:00

abstract：:Although physical fitness is a powerful prognostic marker in clinical medicine, most cardiovascular population-based studies do not have a direct measurement of cardiorespiratory fitness. In line with the call from the National Heart Lung and Blood Institute for innovative, low-cost, epidemiologic studies leveraging e...

journal_title：Clinical cardiology

authors： Al-Mallah MH,Keteyian SJ,Brawner CA,Whelton S,Blaha MJ

更新日期：2014-08-01 00:00:00

abstract：:The Randomized Endo-vein Graft Prospective (REGROUP) trial (ClinicalTrials.gov NCT01850082) is a randomized, intent-to-treat, 2-arm, parallel-design, multicenter study funded by the Cooperative Studies Program (CSP No. 588) of the US Department of Veterans Affairs. Cardiac surgeons at 16 Veterans Affairs (VA) medical ...

journal_title：Clinical cardiology

authors： Zenati MA,Gaziano JM,Collins JF,Biswas K,Gabany JM,Quin JA,Bitondo JM,Bakaeen FG,Kelly RF,Shroyer AL,Bhatt DL

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular events following acute coronary syndrome (ACS). The underlying pathobiology and optimal treatments for this population continue to be evaluated. HYPOTHESIS:Patients with CKD will receive fewer evidence-based therapies and ex...

journal_title：Clinical cardiology

authors： Rhee JW,Wiviott SD,Scirica BM,Gibson CM,Murphy SA,Bonaca MP,Morrow DA,Mega JL

更新日期：2014-06-01 00:00:00

abstract：:Patients with acute coronary syndrome (ACS) usually receive acetylsalicylic acid plus an adenosine diphosphate (ADP) receptor inhibitor to reduce the long-term risk of recurrent events. However, patients receiving standard antiplatelet prophylaxis still face a substantial risk of recurrent events. Strategies involving...

journal_title：Clinical cardiology

authors： Goto S,Tomita A

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Although atrial fibrillation (AF) occurs frequently in patients hospitalized with acute coronary syndrome (ACS), strategies for prevention of thromboembolic complications are poorly characterized. HYPOTHESIS:We sought to examine exposure to warfarin and P2Y12 inhibitors and clinical outcomes among patients ...

journal_title：Clinical cardiology

authors： Jones WS,Mi X,Patel MR,Mills R,Hernandez AF,Curtis LH

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The effect of body fat distribution on left ventricular (LV) mass and geometry has been recently recognized. However, data regarding circulating inflammatory markers in relation to regional visceral fat deposits, which are metabolically active tissues that can impact cardiac structural remodeling, remain spa...

journal_title：Clinical cardiology

authors： Lai YH,Liu CC,Kuo JY,Hung TC,Wu YJ,Yeh HI,Bulwer BE,Hung CL

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:An acute-phase response in patients with acute myocardial infarction could contribute to the development of anemia. HYPOTHESIS:An association may exist between symptom duration, hemoglobin (Hb) concentration and serum C-reactive protein (CRP) values in patients presenting to an emergency department (ED) wit...

journal_title：Clinical cardiology

authors： Shacham Y,Leshem-Rubinow E,Ben-Assa E,Roth A,Steinvil A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia improves survival for selected patients who remain comatose after cardiac arrest. Hypothermia triggers changes in electrocardiographic (ECG) parameters; however, the association of these changes to in-hospital mortality remains unclear. HYPOTHESIS:QT interval changes induced by thera...

journal_title：Clinical cardiology

authors： Lam DH,Dhingra R,Conley SM,Kono AT

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Assessment of patients with aortic stenosis (AS) and impaired left ventricular function remains challenging. Aortic valve calcium (AVC) scoring with computed tomography (CT) and fluoroscopy has been proposed as means of diagnosing and predicting outcomes in patients with severe AS. HYPOTHESIS:Severity of ao...

journal_title：Clinical cardiology

authors： Aksoy O,Cam A,Agarwal S,Ige M,Yousefzai R,Singh D,Griffin BP,Schoenhagen P,Kapadia SR,Tuzcu ME

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Checking for lower-extremity edema is important for diagnosing, monitoring, and managing heart failure (HF). However, the characteristics of this sign in the early stages of cardiovascular disease (stage A, as defined by the American College of Cardiology/American Heart Association 2001 chronic HF guidelines...

journal_title：Clinical cardiology

authors： Kataoka H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Due to sensorial autonomic neuropathy, the type and severity of angina pectoris in patients with diabetes mellitus (DM) may be rather different from the type and severity of angina pectoris in patients without DM. HYPOTHESIS:The aim of the study was to understand if angina pectoris is related to extensive c...

journal_title：Clinical cardiology

authors： Celik A,Karayakali M,Erkorkmaz U,Altunkas F,Karaman K,Koc F,Ceyhan K,Kadi H,Avsar A

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) reduce perioperative cardiac events in high-risk patients undergoing cardiovascular surgery. However, there is paucity of data on the role of statins in patients undergoing intermediate-risk noncardiac, nonvascular surgery (NCNVS). HYPOTHESIS:S...

journal_title：Clinical cardiology

authors： Raju MG,Pachika A,Punnam SR,Gardiner JC,Shishehbor MH,Kapadia SR,Abela GS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Emerging biomarkers for acute myocardial infarction (AMI) may enhance conventional risk-prediction algorithms if they are informative and associated with risk independently of established predictors. In this study, we constructed a cohort for testing emerging biomarkers for AMI in managed-care populations us...

journal_title：Clinical cardiology

authors： Cross DS,McCarty CA,Steinhubl SR,Carey DJ,Erlich PM

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Ablation procedures in patients with paroxysmal atrial fibrillation (PAF) includes isolation of all pulmonary veins (PVs). We hypothesized that an approach using an algorithm to detect arrhythmogenic PVs (aPVs) might lead to shorter procedure duration (PD) and fewer proarrhythmic effects (PE). HYPOTHESIS:Is...

journal_title：Clinical cardiology

authors： Fichtner S,Hessling G,Ammar S,Reents T,Estner HL,Jilek C,Kathan S,Büchner M,Dillier R,Deisenhofer I

更新日期：2013-07-01 00:00:00

abstract：:Heart transplantation is the only curative therapy for chronic heart failure, and it plays an important role in the treatment of chronic heart failure with a survival rate of approximately 50% of all patients after 10 years. This has to be kept in mind when alternative therapies enter into our daily routine in treatin...

journal_title：Clinical cardiology

authors： Garbade J,Barten MJ,Bittner HB,Mohr FW

更新日期：2013-07-01 00:00:00

abstract：:Patients with atrial fibrillation (AF) have an increased stroke risk compared with those in sinus rhythm, although the absolute risk for individual patients is modulated by the presence of various additional risk factors. Patient selection for oral anticoagulation for stroke prevention is based on risks of stroke and ...

journal_title：Clinical cardiology

authors： Verheugt FW

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Investigate the usefulness of echocardiography and acoustic cardiography to monitor patients exposed to anthracycline chemotherapy. HYPOTHESIS:Serial echocardiographies to monitor systolic function may not be neccessary in all patients undergoing anthracycline chemotherapy. METHODS:In a prospective study, ...

journal_title：Clinical cardiology

authors： Toggweiler S,Odermatt Y,Brauchlin A,Zander T,Müller A,Zuber M,Winterhalder R,Erne P

更新日期：2013-04-01 00:00:00

abstract：:Surgical ablation procedure can restore sinus rhythm (SR) in patients with atrial fibrillation (AF) undergoing cardiac surgery. However, it is not known whether it has any impact on clinical outcomes. There is a need for a randomized trial with long-term follow-up to study the outcome of surgical ablation in patients ...

journal_title：Clinical cardiology

authors： Straka Z,Budera P,Osmančík P,Vaněk T,Hulman M,Smíd M,Malý M,Widimský P

更新日期：2013-01-01 00:00:00